Many people can’t conceive because the body identifies sperm as an enemy and rejects it.
As the name implies, anti-sperm antibodies are immune system-produced proteins that wrongly view sperm as foreign intruders. Men and women can experience this; however, the reasons and effects are different.
Men can develop anti-sperm antibodies due to infections in the reproductive system, injuries to the testicles, or even after certain surgeries like vasectomies. When sperm comes into contact with blood due to these conditions, the immune system can misinterpret it as a threat leading to antibody production.